Research Studies
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September 5, 2024

Mediterranean Diet Associated with Lower Death Rates in Cancer Survivors

Written By
Medically Reviewed by
Updated On
October 31, 2024

Surviving cancer is a remarkable achievement, and discovering a straightforward method to enhance your chances of living longer is both encouraging and empowering. This isn't just wishful thinking; it's supported by scientific research. 

Adopting the Mediterranean diet, rich in vegetables, whole grains, fruits, nuts, and olive oil, has been linked to significantly lower death rates among long-term cancer survivors. This simple dietary change could transform how survivors maintain their health after treatment.

A 2024 observational study published in JACC: CardioOncology examined the impact of the Mediterranean diet on long-term cancer survivors, focusing on how this diet affects their health and longevity. The study highlights the importance of dietary habits and offers a practical approach for survivors to enhance their post-cancer lifestyle.

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How the Study Was Conducted

The study aimed to determine if the Mediterranean diet could improve survival rates among long-term cancer survivors by reducing all-cause and cardiovascular mortality.

The study involved 802 long-term cancer survivors from the Moli-sani Study in Italy, with an average age of 63 years, including 476 women and 326 men. Researchers collected dietary data using a food frequency questionnaire, recording participants' intake of Mediterranean diet foods over the past year.

The study provided a comprehensive view of how dietary habits influenced survival across different cancer types over an average follow-up period of 12.7 years. Mortality data was tracked and validated through regional health records and death certificates, coded according to the International Classification of Diseases-9th Revision (ICD-9).

Researchers adjusted for age, sex, energy intake, physical activity, socioeconomic status, and medical history. This study provides valuable insights into the Mediterranean diet's significant role in supporting health maintenance and longevity for cancer survivors.

The Findings of the Study

Cancer survivors who closely followed the Mediterranean diet experienced a 32% reduction in overall mortality, significantly lowering their risk of death from all causes.

The risk of dying from cardiovascular diseases was 58% lower for those who followed the diet closely. Participants with high adherence showed notable differences in mortality rates compared to those with low adherence.

It presents data from a study indicating a 58% reduction in cardiovascular mortality for individuals adhering closely to a specific diet, and a 32% reduction in overall mortality for cancer survivors.

Significance of the Findings

  • Offers a straightforward method for cancer survivors to enhance their health and longevity.
  • Provides evidence supporting the Mediterranean diet's benefits, particularly for heart health.
  • Aligns with previous research showing the diet's ability to reduce inflammation and improve heart function.
  • Specifically, it focuses on cancer survivors, making the findings particularly relevant to this group.
  • Highlights the importance of dietary habits in post-cancer care.
  • Can guide healthcare providers and policymakers in developing nutritional guidelines for cancer survivors.
  • Emphasizes the diet's role in reducing cardiovascular mortality in a high-risk population.

Clinical Application

Cancer survivors can improve their diet by incorporating more vegetables, whole grains, fruits, nuts, and olive oil. Healthcare providers should support this by offering resources, personalized meal plans, and regular follow-ups to monitor progress and health outcomes.

Limitations of the Study

The study's observational nature means it cannot definitively prove that the Mediterranean diet directly causes reduced mortality rates, and the reliance on self-reported dietary data could introduce bias. 

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Additionally, the findings are based on an Italian population, which may limit their applicability to other groups with different dietary habits.

Furthermore, the potential for reporting bias exists as participants might inaccurately recall or report their food intake. These factors highlight the need for caution in generalizing the study's conclusions without further corroboration.

Functional Medicine Labs for Evaluating Mediterranean Diet Effects

Functional medicine labs focusing on nutrition and cardiovascular health offer various tests and panels to assess dietary impacts and monitor heart health. Here are some relevant options available through Rupa Health:

DNA Diet by DNA Life

This test analyzes genetic factors influencing dietary needs and responses, providing personalized nutrition advice to optimize diet and health outcomes.

Oxidized LDL by Doctor's Data

This test measures oxidized low-density lipoprotein (ox-LDL) levels to assess cardiovascular risk and inflammation, which is crucial for heart health monitoring.

NMR LipoProfile by Access Medical Labs

This profile evaluates lipoprotein particles to provide detailed insights into cholesterol levels and cardiovascular health.

Lipid Panel (Basic) by BostonHeart Diagnostics

A comprehensive lipid profile test that measures cholesterol and triglyceride levels to assess heart health and monitor cardiovascular risk.

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Key Takeaways

  • Adhering to the Mediterranean diet can significantly lower the risk of death for long-term cancer survivors, providing an effective approach to enhancing survival rates.
  • The diet is particularly beneficial in reducing the risk of cardiovascular death, highlighting its role in protecting heart health.
  • This study emphasizes the importance of diet in post-cancer care, offering a practical method for survivors to improve their health by incorporating more veggies, whole grains, fruits, nuts, and olive oil into their meals.
The information in this article is designed for educational purposes only and is not intended to be a substitute for informed medical advice or care. This information should not be used to diagnose or treat any health problems or illnesses without consulting a doctor. Consult with a health care practitioner before relying on any information in this article or on this website.

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Lab Tests in This Article

Blake, K. (2023, December 15). The power of functional foods in cancer prevention. Rupa Health. https://www.rupahealth.com/post/the-power-of-functional-foods-in-cancer-prevention

Cloyd, J. (2023, May 17). The Role Of Nutrition And Dietary Supplements In Preventing And Managing Cardiovascular Disease. Rupa Health. https://www.rupahealth.com/post/the-role-of-nutrition-and-dietary-supplements-in-preventing-and-managing-cardiovascular-disease

Creedon, K. (2022, February 15). 6 lifestyle factors that affect longevity. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-longevity

DNA Diet by DNAlife. (n.d.). Rupa Health. Retrieved July 24, 2024, from https://www.rupahealth.com/lab-tests/dnalife-dna-diet

Lipid Panel Basic by BostonHeart Diagnostics. (n.d.). Rupa Health. https://www.rupahealth.com/lab-tests/bostonheart-lipid-panel-basic

Malani, S. (2023, March 8). What is integrative oncology and how can it help your cancer journey? Rupa Health. https://www.rupahealth.com/post/what-is-integrative-oncology-and-how-can-it-help-your-cancer-journey

Marialaura Bonaccio, Augusto Di Castelnuovo, Costanzo, S., Ruggiero, E., Esposito, S., Panzera, T., Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, & Iacoviello, L. (2024). Mediterranean Diet Is Associated With Lower All-Cause and Cardiovascular Mortality Among Long-Term Cancer Survivors. JACC. CardioOncology. https://doi.org/10.1016/j.jaccao.2024.05.012

Monllor-Tormos, A., García-Vigara, A., Morgan, O., García-Pérez, M.-Á., Mendoza, N., Tarín, J. J., & Cano, A. (2023). Mediterranean diet for cancer prevention and survivorship. Maturitas, 178, 107841. https://doi.org/10.1016/j.maturitas.2023.107841

National Cancer Institute. (2021, October 11). What Is Cancer? National Cancer Institute; National Institutes of Health. https://www.cancer.gov/about-cancer/understanding/what-is-cancer

NMR LipoProfile by Access Med Labs. (n.d.). Rupa Health. https://www.rupahealth.com/lab-tests/access-medical-labs-nmr-lipoprofile

Oxidized LDL | rupa health. (2020). Rupa Health. https://www.rupahealth.com/biomarkers/oxidized-ldl

Oxidized LDL by Doctor's Data. (n.d.). Rupa Health. https://www.rupahealth.com/lab-tests/doctors-data-oxidized-ldl

Total cholesterol. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/total-cholesterol-d8055

Triglycerides. (n.d.). Rupa Health. https://www.rupahealth.com/biomarkers/triglycerides

Weinberg, J. L. (2022, November 16). 4 Science Backed Health Benefits of The Mediterranean Diet. Rupa Health. https://www.rupahealth.com/post/4-science-backed-health-benefits-of-the-mediterranean-diet

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