Case Study: Using A GPL-Tox Test To Address Erectile Disfunction

Justine Thorner
Case Study: Using A GPL-Tox Test To Address Erectile Disfunction

Functional Lab Work Case Study

Presented By: Dr. Serraiocco, MD, IFMCP

Dr. Serraiocco, MD
  • Sutter PAMF Integrative Medicine
  • 16 years in practice
  • Board certified in Internal Medicine & Integrative Medicine 

Patient Presentation

  • 48 y/o Male in excellent health 
  • Cardio & weights three times a week
  • Smoothie every morning
  • BMI 24
  • ℅ low libido, erectile dysfunction, fatigue
  • No s/sx psycho-emotional cause 


Lab Results

Interpretation of Labs:

  • Low testosterone levels, but why?
  • Great Plains GPL-tox lab revealed an incredibly high toxin load, some of which are known endocrine disruptors.

Treatment Plan

  • Detox smoothie daily (veggies)
  • Sauna (goal: 45 minutes, 3-5 times a week)
  • Optimal Detox Powder (Seeking Health) prior to Sauna
  • NAC 600mg twice a day (in addition to Optimal Detox Powder)

Patient Follow-up after 6 Months:

The patient was compliant! He had his daily detox veggie smoothie. He used a Steam Room instead of a Sauna because he did not have access to one. He did this 25 minutes 2-3 times a week. He took his Optimal Detox Powder (Seeking Health) prior to steam room, and his NAC everyday.

The patient reported increased energy and muscle mass. He had a full return of libido and erectile function after 2 months. I repeated his GPL-tox lab and the results were much improved.

Overall, this patient had phenomenal results!

Dr. Serraiocco utilized the Great Plains GPL-Tox Profile test.


  • Screens for 173 different environmental pollutants using 18 different metabolites, all from a single urine sample.
  • Uses the power of advanced mass spectrometry (MS/MS), which is necessary to detect lower levels of certain genetic, mitochondrial, and toxic chemical markers that conventional mass spectrometry often misses.
  • Also includes Tiglylglycine, a marker for mitochondrial damage, which is often seen in chronic toxic chemical exposure.

Through the utilization of Speciality Lab work combined with [standard blood tests], Dr. Serraiocco was able to get to the bottom of what was causing this patients issue, support him in resolving it. She re-pulled the test 6 months later, and it showed improved results!

Dr. Serraiocco mentioned another fascinating case to us, where toxins played heavy role. The case was of a woman who had been on disability for 30ish years for an "MS-like illness" causing muscle weakness, brain fog and fatigue.  She went to Caltech University, yet she couldn't calculate a tip on a bill! She had a very heavy toxin load that Dr. Serraiocco was able to see utilizing the same GPL-Tox profile, and after 2 years of lifestyle changes and detox, she gained so much more of her life back. She no longer needed to use a cane, no longer needed to take naps in the afternoon, she was able to take road trips, her cognition  returned and she even started writing a book!

Dr. Serraiocco mentioned to us that she notices high toxin levels in many of my "idiopathic peripheral neuropathy" patients. Some of them reverse with detox.

To learn more about Great Plains Laboratory and the tests they offer, visit the Rupa Health Lab Test Catalog and select Great Plains as the Lab Company. From here you can see the specimen type and more details on each test. If you're a Rupa Practitioner, you can also view the cost of each test.

Not yet a Rupa Practitioner? It’s free to sign up here.

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Justine Thorner
Head of Marketing and Sales at Rupa Health, Holistic Health Coach, Doula, and Birth Coach
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