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4 Specialty Labs You Can Request During Pregnancy to Optimize Your Health

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4 Specialty Labs You Can Request During Pregnancy to Optimize Your Health

3.6 million babies were born in the US in 2020. While pregnancy is often associated with being a time of extreme joy and excitement, it is essential to remember that it also requires a great deal of attention, energy, and nutrients from the mom-to-be.

Pregnancy can be taxing to the body, especially if there are not enough building blocks (i.e., nutrition and healthy hormones) in the mother's body to support all of the changes and requirements needed.

A functional medicine approach to prenatal care involves a deeper look at how the total health of mother and baby can be optimized for this special time of life.


Common Prenatal Complications

Because pregnancy requires so much from the mother's body, some medical conditions are more prevalent during pregnancy. Some examples of these conditions are:

Other Conditions Often Overlooked during Prenatal Care

Micronutrient Deficiencies

Vitamin, mineral, and overall nutritional deficiencies are common during pregnancy since the fetus requires many of the mother's nutrients for growth.

Iron Deficiency Anemia (IDA) is caused by either a low intake of iron or inadequate absorption of the iron we are consuming. A woman's body requires extra iron for pregnancy-related mechanisms, so deficiency is expected at this time.

Furthermore, vitamins A, C, D, E, K, and B6, folate, choline, and minerals including iron, potassium, calcium, magnesium, and zinc are commonly found to be out of balance in pregnant women. Due to these studies, many practitioners request improved dietary guidance to help pregnant women meet but not exceed nutritional recommendations.

Gut Health

Intestinal dysbiosis occurs when the microbiome is out of balance. When this is present, especially during pregnancy, it can disrupt the function of other internal organs, which disturbs our overall delicate physiological balance. This could lead to pregnancy complications. Another reason to focus on gut health during pregnancy is over 63% of an infant's bacterial microbiome can be traced back to their mother's gut microbiota at the time of birth. Therefore focusing on the microbiome during pregnancy can make a massive difference in the mother's and newborn's overall health.


Hormones such as estrogen and progesterone must be circulating during pregnancy in precise amounts to keep the pregnancy healthy. If these two hormones are not at optimal levels, it could lead to a hormone imbalance, negatively affecting the pregnancy significantly.

Genetic Markers

Certain women may also be genetically prone to pregnancy-related complications. One specific example is if the mom has genetic markers that negatively influence her ability to methylate. Methylation is a process that can modify DNA, which means that if it is something that the mother's body is struggling to do effectively, it could impact maternal and fetal health during pregnancy.

Conventional Prenatal Labs

During pregnancy, working with a specialist to monitor maternal and fetal health is essential. An obstetrician (OB) or a midwife are both professional options.

When pregnancy is suspected, an hCG test is performed either through a urine or blood test to confirm the pregnancy.

Then, typically as soon as pregnancy is discovered, a prenatal blood panel is ordered by your midwife or OB to answer some questions about the mother's health status in these early days of pregnancy.

This panel usually includes:

  • ABO blood type to confirm the mother's blood type
  • Rh type to determine if there is a chance that the fetus's blood type is incompatible with the mother's blood type
  • Complete Blood Count to check for signs of anemia
  • Rubella IgG to make sure that the mother has enough antibodies against Rubella
  • RPR, a screening test for syphilis

4 Functional Medicine Labs You Can Request During Pregnancy

Functional medicine can help us answer some questions about why certain pregnancy-related complications occur and how to counteract them.

1. Micronutrient Panel

Understanding the full nutritional status of the mother during pregnancy is very helpful. A Micronutrients Panel can help rule out potential dietary deficiencies or excesses.

2. Comprehensive Stool Test

A comprehensive stool test will give the patient an overview of her microbiome and suggestions on supporting it during pregnancy to increase beneficial bacteria.

3. Hormones

Testing hormones during pregnancy can be a simple way to determine if the balance of the essential reproductive hormones - estrogen, progesterone, and testosterone - are in appropriate ranges for pregnancy.

4. DNA

Evaluating the mother's DNA may be a beneficial way to individualize aspects of health such as methylation status and nutrition. GrowBaby is a genetic test that provides valuable insights into optimizing health outcomes for mom and baby using gene-based personalized diet, supplements, and lifestyle interventions.

Functional Medicine Treatments for Prenatal Care

A functional approach to prenatal care is about optimizing the health of both mom and baby and perhaps preventing various pregnancy-related complications when possible.


During pregnancy, there are vital nutrients that should be consumed in adequate amounts by the mother. Some top nutrients are folate, iron, calcium, vitamin D, iodine, choline, and omega 3, along with healthy sources of fat, protein, and carbohydrates.

Food sources of the common nutrients are:

  • Folate: Legumes, leafy green vegetables, broccoli, asparagus, avocado
  • Heme iron: meat (beef, pork, lamb, etc.), poultry (chicken, turkey), fish, and seafood
  • Non-heme iron: eggs, legumes, tofu, nuts, seeds, and grains
  • Calcium: dairy, seeds, sardines, canned salmon, beans, lentils, nuts, leafy greens
  • Vitamin D: ​​Dairy products and fish, including salmon, herring, and rainbow trout
  • Iodine: seaweed, eggs, freshwater fish
  • Choline: Eggs, beef, chicken, fish, dairy, cruciferous vegetables, leafy greens, beans, nuts, and seeds
  • Omega 3: Salmon, herring, Atlantic mackerel, sardines, rainbow trout, walnuts, and flaxseeds
  • Fats: nuts, seeds, coconut oil and coconuts, olive oil and olives, wild-caught fish, avocados, eggs, grass-fed beef, and beef organs, pasture-raised poultry
  • Protein: wild-caught fish, grass-fed meat, pasture-raised poultry, organic non-GMO nuts, seeds, beans, and legumes
  • Carbohydrates: Organic fresh fruit and vegetables, whole grains, potatoes, wild and brown rice


Although food is an excellent primary source of nutrients, a high-quality prenatal vitamin is also commonly recommended to help fill in any possible gaps in the mother's nutrition.

DHA is essential for brain and eye development. Studies show that supplementing with DHA leads to healthier pregnancy outcomes.

A probiotic is also essential to help keep mom's microbiome healthy and happy. A healthy microbiome is associated with a reduction of pregnancy-related complications.

Balancing your hormones naturally via lifestyle adjustments is a good and safe way to maintain healthy hormone levels during pregnancy. Some simple recommendations are to eat protein at every meal, exercise regularly (in an approved manner and amount as per your physician or midwife), and maintain moderate weight (weight gain is expected during pregnancy but speak with your physician or midwife about how much weight is appropriate for you to gain specifically), be mindful about gut health, lower your sugar intake, try to reduce stress, eat healthy fats, get high-quality sleep consistently, and make sure there is enough fiber in your diet.

If, after a DNA test, it is apparent that the pregnant woman has genetic variants towards methylation issues, it would make sense to supplement with methyl nutrients. This is important because methylation is required to turn on or turn off various genes. Some examples of methyl nutrients are:

  • Folate (vitamin B9)
  • Riboflavin (vitamin B2)
  • Cobalamin (vitamin B12)
  • Pyridoxine (vitamin B6)
  • Choline (vitamin B4)
  • As well as methionine and betaine


While a conventional approach typically monitors the prenatal period, functional medicine can help optimize and maintain maternal and fetal health.

Functional medicine labs are great additional options to labs that an OB or midwife may already order. They can help individuals take an even deeper look into the details of their health that may otherwise go unnoticed such as nutrient status, microbiome health, and DNA information.

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.
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Lab Tests in This Article

  1. 4 common pregnancy complications. (2021, August 8). Johns Hopkins Medicine, based in Baltimore, Maryland.
  2. Adams, J. B., Kirby, J. K., Sorensen, J. C., Pollard, E. L., & Audhya, T. (2022). Evidence based recommendations for an optimal prenatal supplement for women in the US: Vitamins and related nutrients. Maternal Health, Neonatology and Perinatology, 8(1).
  3. Bailey, R. L., Pac, S. G., Fulgoni, V. L., Reidy, K. C., & Catalano, P. M. (2019). Estimation of total usual dietary intakes of pregnant women in the United States. JAMA Network Open, 2(6), e195967.
  4. Carlson, S. E., Colombo, J., Gajewski, B. J., Gustafson, K. M., Mundy, D., Yeast, J., Georgieff, M. K., Markley, L. A., Kerling, E. H., & Shaddy, D. J. (2013). DHA supplementation and pregnancy outcomes. The American Journal of Clinical Nutrition, 97(4), 808-815.
  5. Das, J., & Maitra, A. (2021). Maternal DNA methylation during pregnancy: A review. Reproductive Sciences, 28(10), 2758-2769.
  6. Hamilton, B., Martin, J., & Osterman, M. (2021). Births: Provisional data for 2020.
  7. Hyperemesis Gravidarum: Symptoms & treatment. (2020, December 2). Cleveland Clinic.
  8. Kuang, L., & Jiang, Y. (2019). Effect of probiotic supplementation in pregnant women: A meta-analysis of randomised controlled trials. British Journal of Nutrition, 123(8), 870-880.
  9. Kumar, P., & Magon, N. (2012). Hormones in pregnancy. Nigerian Medical Journal, 53(4), 179-183.
  10. Lang, A. (2022, January 31). 10 natural ways to balance your hormones. Healthline.
  11. Preconception and pregnancy: A nutritional guide for clinicians. (2022, February 18). Naturopathic Doctor News and Review.
  12. Preeclampsia - Symptoms and causes. (2022, April 15). Mayo Clinic.
  13. Weakness, pale skin, and headache are signs of this mineral deficiency. (2022, March 8). Rupa Health | A simpler way to order specialty labwork.
  14. What health problems can develop during pregnancy? (2017, January 31).
  15. Zhang, D., Huang, Y., & Ye, D. (2015). Intestinal dysbiosis: An emerging cause of pregnancy complications? Medical Hypotheses, 84(3), 223-226.
  16. Łoboś, P., & Regulska-Ilow, B. (2021). Link between methyl nutrients and the DNA methylation process in the course of selected diseases in adults. Roczniki Państwowego Zakładu Higieny, 123-136.
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