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A Functional Medicine Approach to Jaundice

Why This Was Updated?

Our specialists regularly review advancements in health and wellness, ensuring our articles are updated with the newest information as it becomes accessible.
Medically Reviewed by

Jaundice occurs when the skin, mucus membranes, and whites of the eyes (sclera) turn yellow due to elevated levels of bilirubin in the body. It can also be accompanied by darkening of the urine and lighter than normal stool color. This hyperbilirubinemia can occur due to increased production or impaired excretion of this waste product. 

Jaundice is common in newborn babies, occurring in around 60 percent of term and 80 percent of preterm babies during the first week of life. Adult jaundice is much less common but is often a sign of a more serious underlying disease.

A functional medicine approach to jaundice focuses on discovering the underlying causes and devising a holistic treatment plan tailored to the individual.

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What is Jaundice?

Bilirubin is a metabolite of heme (ferroprotoporphyrin IX) which helps to bind iron in various proteins like hemoglobin inside red blood cells. The majority (80%) of bilirubin is made by breaking down hemoglobin from red blood cells and destroying erythroid cells in the bone marrow. The rest of the bilirubin in your body is derived from breaking down other heme-containing proteins like myoglobin, cytochromes, catalase, peroxidase, and tryptophan pyrrolase found in the muscles and liver. 

It shows bilirubin’s pathway from albumin-bilirubin to skin, mucous membranes, and eyes, causing yellowing.

Since bilirubin is toxic, your liver filters your blood to pull out waste products like bilirubin which is formed from breaking down red blood cells and combines these and other wastes with bile salts for safe detoxification and excretion. The conjugated bile is normally sent to the gallbladder and secreted into the intestines to help break down fats and be excreted from the body. Since bilirubin has a yellow-orange color, it contributes to the distinctive yellow color of bile, stool, and urine.

Bilirubin is made up of unconjugated (indirect) and conjugated (direct) components. Elevation of either of these components can result in jaundice and the ratio varies depending on if the cause is pre-hepatic, hepatic, or post-hepatic.

The earliest sign that bilirubin is starting to become somewhat elevated is the yellowing of the whites of the eyes (scleral icterus) due to their high elastin content which has an affinity for bilirubin. If levels of bilirubin continue to rise, the skin and mucous membranes can progressively become bright yellow. If the issue persists and is long-standing, the tissues may take on a more apple-green color due to biliverdin. 

What Causes Jaundice?

Bilirubin can start to deposit in body tissues due to processes that increase the production of bilirubin and/or issues with the liver processing and/or excreting this waste product like cirrhosis, hepatitis, primary biliary cholangitis, tumors, and gallstones.

Jaundice is classified into three different categories based on what is causing the elevation of bilirubin including pre-hepatic, intra-hepatic, or post-hepatic (obstructive) jaundice. 

When jaundice occurs due to increased production of bilirubin that exceeds the liver’s ability to conjugate the bilirubin and excrete it into the gut this is classified as pre-hepatic jaundice and is predominantly unconjugated hyperbilirubinemia. The most common cause of this type of jaundice is hemolytic anemia where red blood cells are destroyed resulting in excess heme breakdown and it can also occur with malaria and reabsorbed hematomas.

Intra-hepatic issues can cause jaundice during the production of bilirubin in the liver due to diseases that cause an inability to either conjugate or excrete bilirubin. These include hepatitis A and C, Epstein-Barr virus (infectious mononucleosis), alcohol, genetic metabolic disorders, autoimmune hepatitis, and medicine such as acetaminophen (Tylenol), penicillins, oral contraceptives, chlorpromazine (Thorazine®) and estrogenic or anabolic steroids.  

Jaundice due to post-hepatic causes occurs because there is obstruction of the bile ducts by gallstones, inflammation such as occurs with pancreatitis, parasites, or cancer blocking already produced bilirubin. 

Functional Medicine Perspective on Jaundice

Early recognition and diagnosis of contributing factors to jaundice in older children and adults are important to allow for interventions that improve physiologic functioning and help prevent complications. Functional medicine seeks to identify the root causes of jaundice, rather than just treating symptoms. 

Infant jaundice is worked up by pediatricians and is routinely screened for after birth. Bilirubin levels usually peak between the third and seventh day after birth, so babies should be examined for jaundice during this time. The guidelines presented in this article are focused on jaundice in older children and adults.

A functional medicine approach to jaundice in older children and adults approaches individual factors contributing to health from many aspects. This personalized, root-cause-oriented approach to jaundice looks at the patient’s overall health and addresses her as a whole person. 

This includes listening to the patient and taking a thorough personal and family history. It also includes evaluating aspects that can contribute to conditions that lead to jaundice like diet, genetics, hormonal changes, and lifestyle elements. In addition, a complete physical examination can uncover signs of liver disease such as bruising, spider angiomas (abnormal collection of blood vessels near the surface of the skin), palmar erythema (red coloration of the palms and fingertips), or fluid in the abdomen (ascites) that may give clues to the causes of jaundice.

A holistic approach to jaundice appreciates the role that lifestyle factors like diet and alcohol use can play in the development of conditions that cause jaundice and addresses these elements as part of a comprehensive plan to manage disease can be used to adopt a whole-person approach. Diet, supplementation, lifestyle, and integrative therapies can be used to help prevent progression and reduce inflammation.

Not only does this help to address the underlying causes of jaundice such as improving liver function, reducing inflammation, and calming autoimmunity, but it also helps the entire body come into better balance and improves quality of life overall. 

Diagnostic Testing in Functional Medicine

The causes of jaundice can be assessed using diagnostic testing. Tests used in functional medicine including liver function tests, bilirubin tests, and imaging studies can help to establish the root cause(s) of jaundice. Utilizing these tests can help with understanding the underlying mechanisms causing hyperbilirubinemia and guide treatment.

Tests of liver function can help establish any hepatic dysfunction. This includes measuring levels of enzymes that reflect liver damage such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) as well as testing to measure protein levels and blood clotting abilities. The Hepatic Function Panel by Access Med Labs analyzes a variety of important liver health markers to investigate overall hepatic function and look at levels of both direct and indirect bilirubin. 

Normal serum levels of bilirubin are less than 1 milligram per deciliter (mg/dL) with jaundice appearing first as scleral icterus when levels exceed 3 mg/dl. The ratio of direct (or conjugated) bilirubin and indirect (unconjugated) bilirubin can help narrow down the causes of jaundice. For example, post-hepatic jaundice caused by obstruction of the bile ducts will have primarily direct or conjugated elevated bilirubin with the direct bilirubin accounting for more than 50% of the total bilirubin and may also show elevated alkaline phosphatase. Unconjugated bilirubin usually dominates with pre-hepatic causes of jaundice like hemolytic anemias, autoimmune disorders, drugs, and defects in hemoglobin structure such as sickle cell disease and the thalassemias as well as from some intrahepatic causes that impair enzyme metabolism and the ability for the liver to carry out the conjugation process.

Bilirubin can also be detected in the urine. A urinalysis that is positive for bilirubin indicates that the patient has conjugated jaundice.

Comprehensive stool testing can be a valuable part of functional medicine assessments for jaundice. The GI-MAP + Zonulin from Diagnostic Solutions can be used to evaluate many of the underlying contributors of inflammation and autoimmunity that can impact the liver and bile ducts, including microbial imbalances, digestion, and immune function.

Imaging studies like ultrasound, CT scan, and MRI scan can be utilized to further investigate the structure of the biliary system and liver.

[signup]

Dietary and Nutritional Interventions

Dietary and nutritional interventions are an important part of a holistic approach to managing jaundice and supporting liver health. Dietary choices can aid in detoxification and support healthy liver function. This involves emphasizing foods that are rich in antioxidants and support the liver’s functioning and avoiding substances that add burden to the work of the liver.

An anti-inflammatory diet that emphasizes nutrient-dense foods like whole fresh fruits and vegetables, fatty fish, and olive oil like the Mediterranean diet provides a wide variety of micronutrients that the liver needs for optimal detoxification and functioning. Consuming a range of colorful produce helps you eat antioxidants like polyphenols. These phytonutrients provide powerful anti-inflammatory benefits, support a healthy microbiome, and have a potent antioxidant capacity that allows them to combat harmful free radicals and prevent damage to cells from oxidative damage, protecting liver health. 

This way of eating avoids processed meats, refined sugars and sugary beverages, ultra-processed foods, inflammatory fats like trans fats, and refined grains to reduce inflammation, nourish the microbiome, and improve liver health. 

Incorporating foods rich in natural probiotics like kimchi and sauerkraut into your diet can also help support liver health while boosting a diverse microbiome. Probiotic-rich foods and supplementation can help to heal the intestinal barrier, reduce inflammation, and decrease bacterial toxins such as lipopolysaccharides (LPS) that can pass from the gut to the liver and add to its toxic burden.

Herbal and Natural Remedies

Natural treatments for liver health support liver function and help to address jaundice. Herbal remedies for jaundice include milk thistle, dandelion root, turmeric, and many traditional herbal preparations. Because these treatments can have potential interactions and side effects, it is important to always consult with healthcare professionals before using these remedies to tailor a plan of care that works for your unique needs.Herbal remedies are part of many traditional healing modalities and offer treatment options for some types of jaundice. 

Milk thistle (Silybum marianum) has traditionally been used to address liver conditions in many practices. This herb has immunomodulatory, antioxidant, and antifibrotic effects that make it protective of the liver. Studies suggest that this herb can benefit liver function in alcohol-related liver disease, toxin-induced liver disease, viral liver disease, and primary biliary cholangitis at a dose of 140 mg three times daily.

Curcuma longa is a plant-based medicine derived from turmeric that can support the liver due to its anti-inflammatory properties. It may be especially helpful in cases of jaundice due to bile duct injury and biliary fibrosis

Another herbal remedy that can benefit liver health is dandelion root (Taraxacum officinale). The phytochemicals in this plant are protective of the liver and help reduce oxidative stress that can lead to liver damage and jaundice. Dandelion is also a bitter herb that can increase bile flow.

Yin Zhi Huang is an herbal preparation of Artemisia capillaris and three other herbs that are traditionally used in Traditional Chinese Medicine (TCM) to prevent and treat neonatal jaundice by facilitating the clearance of bilirubin. 

The ancient Indian medicine of Ayurveda also addresses jaundice with plant-based medicines. Ayurveda describes jaundice as “Pandu-roga” meaning yellowish pale, or white disease in Sanskrit. Within this tradition, various methods like emesis, evacuation of the bowels, medicated ghee, a diet rich in rice, wheat, barley, and broth of Mung leaves, and various herbs are used to restore the body to balance. Plants such as ginger, curcumin/turmeric, and Picrorhiza kurroa are used to treat jaundice.

Lifestyle Modifications

Lifestyle factors can have a significant impact on jaundice and liver health. Lifestyle changes for jaundice include stress management, exercise, and avoiding alcohol and toxins.

The health of the gut is closely linked with the health of the liver via the liver-gut axis. This bidirectional communication network is influenced by lifestyle, dietary, and environmental factors. The balance of microbes in the gut influences inflammation and toxin levels in the blood and modulates how the liver functions. 

Lifestyle factors like stress and sleep have significant impacts on the microbiome and the integrity of the intestinal barrier. Having a leaky gut increases inflammation and the chance of autoimmunity which are involved in many cases of jaundice. 

Incorporate a meaningful stress management practice to support your liver health. Mind-body approaches such as yoga, meditation, prayer, time in nature, and breathwork help to activate your parasympathetic nervous system and shift you into a rest-and-digest mode. Aim for a regular sleep schedule that allows for at least 7-9 hours a night.

Regular moderate exercise is also important for supporting liver health. Moving regularly helps to decrease excess inflammation and can improve intestinal permeability and gut health.

It is also important to avoid drinking alcohol or smoking to reduce the burden on your liver.

Integrating Conventional and Functional Treatments

Since the most effective treatment of jaundice in adults depends on understanding the underlying cause, functional medicine approaches are a valuable part of an integrated approach. Integrating treatments for jaundice that combine conventional medical treatments with functional medicine approaches provides a comprehensive management plan.

This type of holistic and collaborative healthcare approach is more likely to accurately pinpoint underlying factors. For example, a functional medicine history looks at nutrition factors and diet carefully. This can help uncover cases where carotenoderma from excessive consumption of carotene-rich foods like carrots, leafy greens, and tomatoes can cause yellowing of the skin that may look similar to jaundice but spares the whites of the eyes. 

This collaborative approach also supports the implementation of important lifestyle changes such as avoiding alcohol to support liver health and treat jaundice. This is key in cases of jaundice caused by alcoholic hepatitis and other liver disease where the individual must first stop drinking alcohol for the jaundice to be appropriately treated. In addition, certain medications may cause drug-induced liver disease including acetaminophen, penicillins, oral contraceptives, chlorpromazine (Thorazine), and estrogenic or anabolic steroids, so functional medicine can help offer alternatives.

In cases where surgery is needed, functional medicine can complement the conventional treatment by supporting the patient with post-operative recovery. This approach emphasizes nutrients that promote healing and encourages integrative methods for pain management and recovery.

[signup]

A Functional Medicine Approach to Jaundice

Jaundice or hyperbilirubinemia leads to yellow discoloration of body tissues including the sclera, skin, and mucus membranes due to a buildup of excess bilirubin. Functional medicine offers a comprehensive approach to figuring out the underlying causes of jaundice utilizing a careful history and physical examination along with functional medicine testing. This allows for a personalized plan of care to address the individual’s unique needs and rebalance her physiology. 

A multidisciplinary team of care integrating conventional with functional medicine approaches provides a multifaceted approach to effective jaundice management. This holistic management of jaundice incorporates strategies like diet, lifestyle, supplementation, and integrative medicine therapies to address each individual’s unique needs. This approach offers strategies to restore and maintain liver health to address jaundice. 

Jaundice occurs when the skin, mucus membranes, and whites of the eyes (sclera) turn yellow due to elevated levels of bilirubin in the body. It can also be accompanied by darkening of the urine and lighter than normal stool color. This hyperbilirubinemia can occur due to increased production or impaired excretion of this waste product. 

Jaundice is common in newborn babies, occurring in around 60 percent of term and 80 percent of preterm babies during the first week of life. Adult jaundice is much less common but is often a sign of a more serious underlying condition.

A functional medicine approach to jaundice focuses on discovering the underlying factors and devising a holistic plan tailored to the individual.

[signup]

What is Jaundice?

Bilirubin is a metabolite of heme (ferroprotoporphyrin IX) which helps to bind iron in various proteins like hemoglobin inside red blood cells. The majority (80%) of bilirubin is made by breaking down hemoglobin from red blood cells and destroying erythroid cells in the bone marrow. The rest of the bilirubin in your body is derived from breaking down other heme-containing proteins like myoglobin, cytochromes, catalase, peroxidase, and tryptophan pyrrolase found in the muscles and liver. 

It shows bilirubin’s pathway from albumin-bilirubin to skin, mucous membranes, and eyes, causing yellowing.

Since bilirubin is toxic, your liver filters your blood to pull out waste products like bilirubin which is formed from breaking down red blood cells and combines these and other wastes with bile salts for safe detoxification and excretion. The conjugated bile is normally sent to the gallbladder and secreted into the intestines to help break down fats and be excreted from the body. Since bilirubin has a yellow-orange color, it contributes to the distinctive yellow color of bile, stool, and urine.

Bilirubin is made up of unconjugated (indirect) and conjugated (direct) components. Elevation of either of these components can result in jaundice and the ratio varies depending on if the cause is pre-hepatic, hepatic, or post-hepatic.

The earliest sign that bilirubin is starting to become somewhat elevated is the yellowing of the whites of the eyes (scleral icterus) due to their high elastin content which has an affinity for bilirubin. If levels of bilirubin continue to rise, the skin and mucous membranes can progressively become bright yellow. If the issue persists and is long-standing, the tissues may take on a more apple-green color due to biliverdin. 

What Causes Jaundice?

Bilirubin can start to deposit in body tissues due to processes that increase the production of bilirubin and/or issues with the liver processing and/or excreting this waste product like cirrhosis, hepatitis, primary biliary cholangitis, tumors, and gallstones.

Jaundice is classified into three different categories based on what is causing the elevation of bilirubin including pre-hepatic, intra-hepatic, or post-hepatic (obstructive) jaundice. 

When jaundice occurs due to increased production of bilirubin that exceeds the liver’s ability to conjugate the bilirubin and excrete it into the gut this is classified as pre-hepatic jaundice and is predominantly unconjugated hyperbilirubinemia. The most common cause of this type of jaundice is hemolytic anemia where red blood cells are destroyed resulting in excess heme breakdown and it can also occur with malaria and reabsorbed hematomas.

Intra-hepatic issues can cause jaundice during the production of bilirubin in the liver due to conditions that cause an inability to either conjugate or excrete bilirubin. These include hepatitis A and C, Epstein-Barr virus (infectious mononucleosis), alcohol, genetic metabolic disorders, autoimmune hepatitis, and medicine such as acetaminophen (Tylenol), penicillins, oral contraceptives, chlorpromazine (Thorazine®) and estrogenic or anabolic steroids.  

Jaundice due to post-hepatic causes occurs because there is obstruction of the bile ducts by gallstones, inflammation such as occurs with pancreatitis, parasites, or cancer blocking already produced bilirubin. 

Functional Medicine Perspective on Jaundice

Early recognition and understanding of contributing factors to jaundice in older children and adults are important to allow for interventions that support physiologic functioning and help prevent complications. Functional medicine seeks to identify the root causes of jaundice, rather than just addressing symptoms. 

Infant jaundice is worked up by pediatricians and is routinely screened for after birth. Bilirubin levels usually peak between the third and seventh day after birth, so babies should be examined for jaundice during this time. The guidelines presented in this article are focused on jaundice in older children and adults.

A functional medicine approach to jaundice in older children and adults approaches individual factors contributing to health from many aspects. This personalized, root-cause-oriented approach to jaundice looks at the patient’s overall health and addresses her as a whole person. 

This includes listening to the patient and taking a thorough personal and family history. It also includes evaluating aspects that can contribute to conditions that lead to jaundice like diet, genetics, hormonal changes, and lifestyle elements. In addition, a complete physical examination can uncover signs of liver disease such as bruising, spider angiomas (abnormal collection of blood vessels near the surface of the skin), palmar erythema (red coloration of the palms and fingertips), or fluid in the abdomen (ascites) that may give clues to the causes of jaundice.

A holistic approach to jaundice appreciates the role that lifestyle factors like diet and alcohol use can play in the development of conditions that cause jaundice and addresses these elements as part of a comprehensive plan to manage health. Diet, supplementation, lifestyle, and integrative therapies can be used to help support liver function and reduce inflammation.

Not only does this help to address the underlying factors of jaundice such as supporting liver function, reducing inflammation, and calming autoimmunity, but it also helps the entire body come into better balance and improves quality of life overall. 

Diagnostic Testing in Functional Medicine

The factors contributing to jaundice can be assessed using diagnostic testing. Tests used in functional medicine including liver function tests, bilirubin tests, and imaging studies can help to establish the root cause(s) of jaundice. Utilizing these tests can help with understanding the underlying mechanisms causing hyperbilirubinemia and guide management.

Tests of liver function can help establish any hepatic dysfunction. This includes measuring levels of enzymes that reflect liver health such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) as well as testing to measure protein levels and blood clotting abilities. The Hepatic Function Panel by Access Med Labs analyzes a variety of important liver health markers to investigate overall hepatic function and look at levels of both direct and indirect bilirubin. 

Normal serum levels of bilirubin are less than 1 milligram per deciliter (mg/dL) with jaundice appearing first as scleral icterus when levels exceed 3 mg/dl. The ratio of direct (or conjugated) bilirubin and indirect (unconjugated) bilirubin can help narrow down the factors contributing to jaundice. For example, post-hepatic jaundice caused by obstruction of the bile ducts will have primarily direct or conjugated elevated bilirubin with the direct bilirubin accounting for more than 50% of the total bilirubin and may also show elevated alkaline phosphatase. Unconjugated bilirubin usually dominates with pre-hepatic causes of jaundice like hemolytic anemias, autoimmune disorders, drugs, and defects in hemoglobin structure such as sickle cell disease and the thalassemias as well as from some intrahepatic causes that impair enzyme metabolism and the ability for the liver to carry out the conjugation process.

Bilirubin can also be detected in the urine. A urinalysis that is positive for bilirubin indicates that the patient has conjugated jaundice.

Comprehensive stool testing can be a valuable part of functional medicine assessments for jaundice. The GI-MAP + Zonulin from Diagnostic Solutions can be used to evaluate many of the underlying contributors of inflammation and autoimmunity that can impact the liver and bile ducts, including microbial imbalances, digestion, and immune function.

Imaging studies like ultrasound, CT scan, and MRI scan can be utilized to further investigate the structure of the biliary system and liver.

[signup]

Dietary and Nutritional Interventions

Dietary and nutritional interventions are an important part of a holistic approach to managing jaundice and supporting liver health. Dietary choices can aid in detoxification and support healthy liver function. This involves emphasizing foods that are rich in antioxidants and support the liver’s functioning and avoiding substances that add burden to the work of the liver.

An anti-inflammatory diet that emphasizes nutrient-dense foods like whole fresh fruits and vegetables, fatty fish, and olive oil like the Mediterranean diet provides a wide variety of micronutrients that the liver needs for optimal detoxification and functioning. Consuming a range of colorful produce helps you eat antioxidants like polyphenols. These phytonutrients provide powerful anti-inflammatory benefits, support a healthy microbiome, and have a potent antioxidant capacity that allows them to combat harmful free radicals and support cell health, protecting liver function. 

This way of eating avoids processed meats, refined sugars and sugary beverages, ultra-processed foods, inflammatory fats like trans fats, and refined grains to reduce inflammation, nourish the microbiome, and support liver health. 

Incorporating foods rich in natural probiotics like kimchi and sauerkraut into your diet can also help support liver health while boosting a diverse microbiome. Probiotic-rich foods and supplementation can help to support the intestinal barrier, reduce inflammation, and decrease bacterial toxins such as lipopolysaccharides (LPS) that can pass from the gut to the liver and add to its toxic burden.

Herbal and Natural Remedies

Natural treatments for liver health support liver function and help to address jaundice. Herbal remedies for jaundice include milk thistle, dandelion root, turmeric, and many traditional herbal preparations. Because these treatments can have potential interactions and side effects, it is important to always consult with healthcare professionals before using these remedies to tailor a plan of care that works for your unique needs. Herbal remedies are part of many traditional healing modalities and offer options for some types of jaundice. 

Milk thistle (Silybum marianum) has traditionally been used to support liver conditions in many practices. This herb has immunomodulatory, antioxidant, and antifibrotic effects that may support liver health. Studies suggest that this herb can benefit liver function in alcohol-related liver conditions, toxin-induced liver conditions, viral liver conditions, and primary biliary cholangitis at a dose of 140 mg three times daily.

Curcuma longa is a plant-based medicine derived from turmeric that can support the liver due to its anti-inflammatory properties. It may be especially helpful in cases of jaundice due to bile duct injury and biliary fibrosis

Another herbal remedy that can support liver health is dandelion root (Taraxacum officinale). The phytochemicals in this plant may support liver health and help reduce oxidative stress that can lead to liver damage and jaundice. Dandelion is also a bitter herb that can increase bile flow.

Yin Zhi Huang is an herbal preparation of Artemisia capillaris and three other herbs that are traditionally used in Traditional Chinese Medicine (TCM) to support the clearance of bilirubin. 

The ancient Indian medicine of Ayurveda also addresses jaundice with plant-based medicines. Ayurveda describes jaundice as “Pandu-roga” meaning yellowish pale, or white condition in Sanskrit. Within this tradition, various methods like emesis, evacuation of the bowels, medicated ghee, a diet rich in rice, wheat, barley, and broth of Mung leaves, and various herbs are used to support the body to balance. Plants such as ginger, curcumin/turmeric, and Picrorhiza kurroa are used to support liver health.

Lifestyle Modifications

Lifestyle factors can have a significant impact on jaundice and liver health. Lifestyle changes for jaundice include stress management, exercise, and avoiding alcohol and toxins.

The health of the gut is closely linked with the health of the liver via the liver-gut axis. This bidirectional communication network is influenced by lifestyle, dietary, and environmental factors. The balance of microbes in the gut influences inflammation and toxin levels in the blood and modulates how the liver functions. 

Lifestyle factors like stress and sleep have significant impacts on the microbiome and the integrity of the intestinal barrier. Having a leaky gut increases inflammation and the chance of autoimmunity which are involved in many cases of jaundice. 

Consider incorporating a meaningful stress management practice to support your liver health. Mind-body approaches such as yoga, meditation, prayer, time in nature, and breathwork help to activate your parasympathetic nervous system and shift you into a rest-and-digest mode. Aim for a regular sleep schedule that allows for at least 7-9 hours a night.

Regular moderate exercise is also important for supporting liver health. Moving regularly helps to decrease excess inflammation and can support intestinal permeability and gut health.

It is also important to avoid drinking alcohol or smoking to reduce the burden on your liver.

Integrating Conventional and Functional Treatments

Since the most effective management of jaundice in adults depends on understanding the underlying factors, functional medicine approaches are a valuable part of an integrated approach. Integrating treatments for jaundice that combine conventional medical treatments with functional medicine approaches provides a comprehensive management plan.

This type of holistic and collaborative healthcare approach is more likely to accurately pinpoint underlying factors. For example, a functional medicine history looks at nutrition factors and diet carefully. This can help uncover cases where carotenoderma from excessive consumption of carotene-rich foods like carrots, leafy greens, and tomatoes can cause yellowing of the skin that may look similar to jaundice but spares the whites of the eyes. 

This collaborative approach also supports the implementation of important lifestyle changes such as avoiding alcohol to support liver health and address jaundice. This is key in cases of jaundice associated with alcoholic hepatitis and other liver conditions where the individual must first stop drinking alcohol for the jaundice to be appropriately managed. In addition, certain medications may cause drug-induced liver conditions including acetaminophen, penicillins, oral contraceptives, chlorpromazine (Thorazine), and estrogenic or anabolic steroids, so functional medicine can help offer alternatives.

In cases where surgery is needed, functional medicine can complement the conventional treatment by supporting the patient with post-operative recovery. This approach emphasizes nutrients that promote healing and encourages integrative methods for pain management and recovery.

[signup]

A Functional Medicine Approach to Jaundice

Jaundice or hyperbilirubinemia leads to yellow discoloration of body tissues including the sclera, skin, and mucus membranes due to a buildup of excess bilirubin. Functional medicine offers a comprehensive approach to figuring out the underlying factors of jaundice utilizing a careful history and physical examination along with functional medicine testing. This allows for a personalized plan of care to address the individual’s unique needs and support her physiology. 

A multidisciplinary team of care integrating conventional with functional medicine approaches provides a multifaceted approach to effective jaundice management. This holistic management of jaundice incorporates strategies like diet, lifestyle, supplementation, and integrative medicine therapies to address each individual’s unique needs. This approach offers strategies to support and maintain liver health to address jaundice. 

The information provided is not intended to be a substitute for professional medical advice. Always consult with your doctor or other qualified healthcare provider before taking any dietary supplement or making any changes to your diet or exercise routine.
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Lab Tests in This Article

American College of Surgeons Division of Education. (n.d.). ACS/ASE Medical Student Core Curriculum Jaundice. https://www.facs.org/media/dwmf1i0m/jaundice.pdf

Blake, K. (2023, May 22). Anti Inflammatory Diet 101: What to Eat and Avoid Plus Specialty Labs To Monitor Results. Rupa Health. https://www.rupahealth.com/post/anti-inflammatory-diet

Ceccherini, E., Cecchettini, A., Morales, M. A., & Rocchiccioli, S. (2020). The Potentiality of Herbal Remedies in Primary Sclerosing Cholangitis: From In Vitro to Clinical Studies. Frontiers in Pharmacology, 11. https://doi.org/10.3389/fphar.2020.00813

Cleveland Clinic. (2018, July 23). Adult jaundice. Cleveland Clinic. https://my.clevelandclinic.org/health/diseases/15367-adult-jaundice

Cloyd, J. (2023a, February 1). 6 anemia types you need to know about. Rupa Health. https://www.rupahealth.com/post/6-different-types-of-anemia-you-may-not-be-aware-of

Cloyd, J. (2023b, February 28). A Functional Medicine Protocol for Leaky Gut Syndrome. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-protocol-for-leaky-gut-syndrome

Cloyd, J. (2023c, April 11). A Functional Medicine Post-Operative Protocol. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-post-operative-protocol

Cloyd, J. (2023d, April 19). What’s the Difference Between Prebiotics vs. Probiotics vs. Postbiotics? Rupa Health. https://www.rupahealth.com/post/whats-the-difference-between-prebiotics-vs-probiotics-vs-postbiotics

Cloyd, J. (2024, January 15). Assessing Liver Function in Detoxification: When to Order Comprehensive Liver Panels. Rupa Health. https://www.rupahealth.com/post/assessing-liver-function-in-detoxification-when-to-order-comprehensive-liver-panels

Conner, V. (2022, July 13). This Virus Has Infected Over 90% of The Adult Population. Yet Many Never Experience Any Symptoms. Rupa Health. https://www.rupahealth.com/post/epstein-barr-virus-ebv

Diorio, B. (2023, January 17). Why Most Functional Medicine Practitioners Say No To Alcohol. Rupa Health. https://www.rupahealth.com/post/why-most-functional-medicine-practitioners-say-no-to-alcohol

Huang, W., Zhang, J., & Moore, D. D. (2004). A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR. Journal of Clinical Investigation, 113(1), 137–143. https://doi.org/10.1172/jci200418385

Joseph, A., & Samant, H. (2023, February 12). Jaundice. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK544252/

Kalakonda, A., John, S., & Jenkins, B. A. (2022, September 12). Physiology, Bilirubin. Nih.gov; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK470290/

Khakham, C. (2023, May 16). Natural Anti-Inflammatory Agents for Gut Health: An Evidence-Based Review. Rupa Health. https://www.rupahealth.com/post/natural-anti-inflammatory-agents-for-gut-health-an-evidence-based-review

LoBisco, S. (2023, January 13). Testing The Liver-Gut Axis For the Integrative Treatment of Liver Disease. Rupa Health. https://www.rupahealth.com/post/testing-the-liver-gut-axis-for-the-integrative-treatment-of-liver-disease

Maholy, N. (2023, April 14). How to reduce stress through mind-body therapies. Rupa Health. https://www.rupahealth.com/post/how-to-reduce-stress-through-mind-body-therapies

Martín-Mateos, R., & Albillos, A. (2021). The Role of the Gut-Liver Axis in Metabolic Dysfunction-Associated Fatty Liver Disease. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.660179

Mayo Clinic. (2018). Infant Jaundice - Diagnosis and Treatment - Mayo Clinic. Mayoclinic.org. https://www.mayoclinic.org/diseases-conditions/infant-jaundice/diagnosis-treatment/drc-20373870

Meir, A. Y., Rinott, E., Tsaban, G., Zelicha, H., Kaplan, A., Rosen, P., Shelef, I., Youngster, I., Shalev, A., Blüher, M., Ceglarek, U., Stumvoll, M., Tuohy, K., Diotallevi, C., Vrhovsek, U., Hu, F., Stampfer, M., & Shai, I. (2021). Effect of green-Mediterranean diet on intrahepatic fat: the DIRECT PLUS randomised controlled trial. Gut, 70(11), 2085–2095. https://doi.org/10.1136/gutjnl-2020-323106

Mulrow, C., Lawrence, V., Jacobs, B., Dennehy, C., Sapp, J., Ramirez, G., Aguilar, C., Montgomery, K., Morbidoni, L., Arterburn, J. M., Chiquette, E., Harris, M., Mullins, D., Vickers, A., & Flora, K. (2000). Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects: Summary. In www.ncbi.nlm.nih.gov. Agency for Healthcare Research and Quality (US). https://www.ncbi.nlm.nih.gov/books/NBK11896/

National Center for Complementary and Integrative Health. (2020, May). Turmeric. NCCIH. https://www.nccih.nih.gov/health/turmeric

National Collaborating Centre for Women's and Children's Health (UK). (2010). Neonatal Jaundice. In PubMed. RCOG Press. https://www.ncbi.nlm.nih.gov/books/NBK65119/

National Institutes of Health. (2020, August). Milk Thistle. NCCIH. https://www.nccih.nih.gov/health/milk-thistle

Petersen, A. M. W., & Pedersen, B. K. (2005). The anti-inflammatory effect of exercise. Journal of Applied Physiology, 98(4), 1154–1162. https://doi.org/10.1152/japplphysiol.00164.2004

Pfingstgraf, I. O., Taulescu, M., Pop, R. M., Orăsan, R., Vlase, L., Uifalean, A., Todea, D., Alexescu, T., Toma, C., & Pârvu, A. E. (2021). Protective Effects of Taraxacum officinale L. (Dandelion) Root Extract in Experimental Acute on Chronic Liver Failure. Antioxidants (Basel, Switzerland), 10(4). https://doi.org/10.3390/antiox10040504

Roche, S. P., & Kobos, R. (2004). Jaundice in the adult patient. American Family Physician, 69(2), 299–304. https://pubmed.ncbi.nlm.nih.gov/14765767/

Sweetnich, J. (2023, May 19). Overview of The Liver 101: Top Conditions, Specialty Testing, and Integrative Medicine Treatment Options. Rupa Health. https://www.rupahealth.com/post/overview-liver-101-top-conditions-and-testing

Tewari, D., Mocan, A., Parvanov, E. D., Sah, A. N., Nabavi, S. M., Huminiecki, L., Ma, Z. F., Lee, Y. Y., Horbańczuk, J. O., & Atanasov, A. G. (2017). Ethnopharmacological Approaches for Therapy of Jaundice: Part I. Frontiers in Pharmacology, 8. https://doi.org/10.3389/fphar.2017.00518

Ticinesi, A., Lauretani, F., Tana, C., Nouvenne, A., Ridolo, E., & Meschi, T. (2019). Exercise and immune system as modulators of intestinal microbiome: implications for the gut-muscle axis hypothesis. Exercise Immunology Review, 25, 84–95. https://pubmed.ncbi.nlm.nih.gov/30753131/

Vanuytsel, T., van Wanrooy, S., Vanheel, H., Vanormelingen, C., Verschueren, S., Houben, E., Salim Rasoel, S., Tόth, J., Holvoet, L., Farré, R., Van Oudenhove, L., Boeckxstaens, G., Verbeke, K., & Tack, J. (2013). Psychological stress and corticotropin-releasing hormone increase intestinal permeability in humans by a mast cell-dependent mechanism. Gut, 63(8), 1293–1299. https://doi.org/10.1136/gutjnl-2013-305690

Weinberg, J. L. (2022a, August 9). These Lifestyle Choices Increase Your Risk Of Gallstones. Rupa Health. https://www.rupahealth.com/post/natural-treatment-for-gallstones-and-gallstone-prevention

Weinberg, J. L. (2022b, October 4). Pancreatitis: Causes, Risk Factors, and Treatments. Www.rupahealth.com. https://www.rupahealth.com/post/pancreatitis-causes-risk-factors-and-treatments

Weinberg, J. L. (2023a, April 17). Treating Bile Acid Diarrhea Naturally With The Help of Integrative Medicine. Rupa Health. https://www.rupahealth.com/post/treating-bile-acid-diarrhea-naturally-with-the-help-of-functional-medicine

Weinberg, J. L. (2023b, September 15). An Integrative Medicine Approach to Autoimmune Hepatitis. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-autoimmune-hepatitis

Weinberg, J. L. (2023c, September 18). Should You Use Herbal Bitters for Digestion? Rupa Health. https://www.rupahealth.com/post/should-you-use-herbal-bitters-for-digestion

Weinberg, J. L. (2023d, October 20). An Integrative Medicine Approach to Primary Biliary Cholangitis. Rupa Health. https://www.rupahealth.com/post/an-integrative-medicine-approach-to-primary-biliary-cholangitis

Weinberg, J. L. (2023e, December 19). The Science of Sleep: Functional Medicine for Restorative Sleep. Rupa Health. https://www.rupahealth.com/post/the-science-of-sleep-functional-medicine-for-restorative-sleep

Weinberg, J. L. (2023f, December 26). The Power of Polyphenols: Functional Medicine’s Antioxidant Superstars. Rupa Health. https://www.rupahealth.com/post/the-power-of-polyphenols-functional-medicines-antioxidant-superstars

Yoshimura, H. (2023a, July 17). Using Functional Medicine As Personalized Medicine. Rupa Health. https://www.rupahealth.com/post/using-functional-medicine-as-personalized-medicine

Yoshimura, H. (2023b, October 12). An Integrative and Complementary Approach to Hepatitis C. Rupa Health. https://www.rupahealth.com/post/an-integrative-and-complementary-approach-to-hepatitis-c

Yoshimura, H. (2023c, October 16). An Integrative Approach to Liver Cirrhosis Management. Rupa Health. https://www.rupahealth.com/post/an-integrative-approach-to-liver-cirrhosis-management

Yoshimura, H. (2023d, October 19). What is Alcohol-Related Liver Disease and How Can Functional Medicine Help? Rupa Health. https://www.rupahealth.com/post/what-is-alcohol-related-liver-disease-and-how-can-functional-medicine-help

Yoshimura, H. (2023e, November 7). The remarkable power of exercise on our health: A comprehensive overview. Rupa Health. https://www.rupahealth.com/post/the-remarkable-power-of-exercise-on-our-health-a-comprehensive-overview

Zhang, L., Yang, L., & Chu, H. (2023). Targeting Gut Microbiota for the Treatment of Primary Biliary Cholangitis: From Bench to Bedside. Journal of Clinical and Translational Hepatology, 000(000). https://doi.org/10.14218/jcth.2022.00408

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