Islet Cell Antibody Screen

The Islet Cell Antibody Screen test detects the presence of autoantibodies targeting the insulin-producing cells in the pancreas. It is primarily used for diagnosing autoimmune type 1 diabetes and identifying individuals at risk of developing the disease. This test is also valuable in distinguishing type 1 diabetes from other forms of diabetes, such as type 2 diabetes or latent autoimmune diabetes in adults (LADA), and in evaluating autoimmune conditions associated with pancreatic dysfunction.

Islet Cell Antibody Screen with Reflex to Titer - Type 1 diabetes is characterized by lymphocytic cell infiltrate of the pancreatic islets. Measurement of GAD-65, ICA-512, and Insulin Antibody is a highly sensitive means to assess risk and predict onset of Type 1 diabetes. There is a correlation between the number of positive antibodies and the antibody titers versus the severity of the autoimmune process.