The lab experience you’re looking for, within a more complete clinical platform. Order, manage, and turn results into personalized plans in one seamless flow. Learn more
Kynurenic Acid, often abbreviated as KYNA, is a naturally occurring compound in your body. It's a byproduct of the metabolism of an amino acid called tryptophan, which you might recognize as the substance in turkey that makes you feel sleepy after a big Thanksgiving meal. But KYNA does much more than just make you feel relaxed. It plays a crucial role in your nervous system, acting as a protective shield for your brain. It does this by blocking certain signals that can overstimulate and potentially harm your brain cells. In essence, KYNA is like a diligent security guard, constantly patrolling your brain to keep it safe and healthy.
If Your Levels Are High
High levels of Kynurenic Acid (KYNA) in your body could indicate a variety of things. For instance, it could mean that your body is metabolizing tryptophan at a higher rate, possibly due to increased intake of foods rich in this amino acid, such as turkey or cheese. Alternatively, it could suggest that your brain is under stress and is producing more KYNA to protect itself. Certain medications, like antipsychotics or antidepressants, can also increase KYNA levels as they can influence the metabolism of tryptophan. Additionally, some health conditions, like schizophrenia or Alzheimer's disease, have been associated with elevated KYNA levels, as these conditions can cause an overstimulation of the brain, leading to increased production of KYNA as a protective response. However, it's important to note that high KYNA levels are not a definitive indicator of any specific condition or factor, but rather a potential sign that your brain is working hard to protect itself.
Symptoms of High Levels
Symptoms of high levels of Kynurenic Acid are not typically noticeable, as KYNA is a protective substance in the brain. However, if the high levels are due to an underlying condition, symptoms related to that condition may be present.
If Your Levels are Low
Low levels of Kynurenic Acid (KYNA) in your body could mean that your brain might not be getting the protection it needs. KYNA is like a bouncer for your brain, keeping out harmful signals that could damage your brain cells. It's made when your body breaks down tryptophan, an amino acid found in foods like turkey. If you're not getting enough tryptophan in your diet, or if your body isn't processing it properly, you might not have enough KYNA. Certain medications, like those used to treat depression or anxiety, can also affect how your body makes and uses KYNA. Low levels could potentially lead to conditions like schizophrenia or Alzheimer's disease, as these conditions have been linked to disruptions in the way the brain processes signals.
Symptoms of Low Levels
Symptoms of low levels of Kynurenic Acid may not be immediately noticeable, as this compound primarily functions within the brain. However, over time, individuals might experience cognitive issues such as memory loss, difficulty concentrating, or changes in mood.
DUTCH Complete (Dried Urine) by Precision Analytical (DUTCH)
Urine
The DUTCH Complete™ is a comprehensive assessment of sex and adrenal hormones and their metabolites and includes the daily, free cortisol pattern, organic acids, melatonin, and 8-OHdG. This test cannot be ordered for patients under 12 years of age.
Organic Acids (OAT) by Mosaic Diagnostics (formerly Great Plains)
Urine
The Organic Acids Test (OAT) provides a comprehensive metabolic analysis of a patient's overall health, including intestinal yeast and bacteria, vitamin and mineral levels, oxidative stress, neurotransmitter levels, and oxalates.
DUTCH Plus by Precision Analytical (DUTCH)
Saliva
Urine
The DUTCH Plus™ offers an extensive assessment of sex and adrenal hormones and their metabolites. It also assesses the Cortisol Awakening Response (CAR) and includes the insomnia cortisol sample. This test cannot be ordered for patients under 12 years of age.
Metabolomix+ by Genova Diagnostics
Urine
The Metabolomix+ combines a variety of tests to analyze key nutritional biomarkers, including organic acids, amino acids, and oxidative stress markers. This test cannot be ordered for patients under two years of age.
NutrEval® Plasma by Genova Diagnostics
Whole Blood
Urine
Serum
Plasma
The NutrEval® Plasma evaluates a variety of antioxidants, vitamins, minerals, fatty acids, and other biomarkers to determine nutritional deficiencies and imbalances. This test cannot be ordered for patients under 2 years of age.