Occludin/Zonulin IgG

Measures IgG, IgM, and IgA antibodies against endotoxins, structural and tight junction proteins. Detects disturbance in gut flora and endotoxemia, breakdown in tight junctions (occludin, zonulin), and cytoskeletal proteins. Some or all of these contribute to leaky gut to large molecules that challenge the immune system. Leaky gut to large molecules is the gateway to autoimmunity and neuroautoimmunity via blood-brain barriers damaged by endotoxins and other factors. Developed, patented, and published by Aristo Vojdani, PhD, MSc, CLS, known as the father of functional immunology, in 2012, 2013, 2014, 2015, 2017, 2019, 2020, and 2024.

Measures antibodies that are part of Leaky Gut Antibodies, Wheat/Gluten Immune Reactivity, and Gluten Cross-Reactive Foods. Detects leaky gut to large molecules, disturbance in the gut flora, wheat- and gluten-associated autoimmunities, and autoimmunities including neuroautoimmunities associated with the consumption of gluten cross-reactive foods, such as MS and type 1 diabetes induced by casein and milk butyrophilin.

Measures IgG, IgA, and IgM antibodies against bacterial toxins, tight junction and cytoskeletal proteins (Array 2, 22), and blood-brain barrier proteins (Array 20).Detects disturbance of gut flora in the small and large intestine, and damage done to the gut and blood-brain structures that set the stage not only for leaky gut and leaky brain, but for the development of SIBO/IBS, inflammation, autoimmunity, neuroautoimmunity, and neurodegenerative disorders.