dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix - The dilute Russell Viper Venom time integrated test is a sensitive method for the detection of Lupus Anticoagulants (LA). LA are autoantibodies that target protein-phospholipid complexes and are found in a variety of clinical conditions. In some patients, a confirmed positive result is associated with an increased thrombotic risk, and is often found in women who have recurrent fetal loss. As Lupus anticoagulants reflect a heterogenous group of antibodies, international consensus guidelines on testing require at least two screening assays be used for a complete evaluation. Refer to Lupus Anticoagulant Comprehensive Evaluation which includes the DRVVT plus a second pathway of testing, the PTT-LA with reflex to Hexagonal Phase Confirm and Thrombin Time.
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