Hepatitis C Viral RNA, Quantitative Real-Time PCR with Reflexes - Hepatitis C (HCV) viral genotype is required prior to the initiation of antiviral therapy with direct acting agents. In addition, the FDA package insert recommends baseline NS5a resistance testing for HCV genotype 1a patients being evaluated for treatment with Zepatier, which contains the NS5a inhibitor elbasvir and the NS3 protease inhibitor grazoprevir.
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