Parvovirus B19 Antibodies (IgG, IgM) - Parvovirus B19 is also known as Fifth Disease. It primarily affects children and causes a rash on the face, trunk, and limbs. Joint pain and swelling is more common in adults. Although one-fifth of those affected have only mild disease, patients with sickle cell anemia or similar types of chronic anemia can suffer from acute anemia. Infection during pregnancy can lead to complications.