Tick-Borne Disease, Antibody Panel - There is substantial clinical overlap among tick-borne diseases caused by Anaplasma, Babesia, Borrelia, and Ehrlichia. Some infections can progress to severe complications such as anemia, hepatitis and pneumonia.. More than one infectious agent may be transmitted by the same tick, and rates of co-infection are not well defined since clinicians may only suspect a single tick-borne disease etiology.