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Anti-DGP IgG
.
Anti-DGP IgG
What's
Anti-DGP IgG
?
Anti-DGP IgG, or Anti-Deamidated Gliadin Peptide Immunoglobulin G, is a special kind of antibody that your immune system creates in response to gliadin, a part of gluten. This antibody is unique because it specifically targets deamidated gliadin, a changed form of gliadin that is more likely to cause an immune reaction. The presence of Anti-DGP IgG in your blood can offer valuable information about how your body is reacting to gluten, making it an important indicator in the study of gluten-related health issues.
If Your Levels Are High
Elevated levels of Anti-DGP IgG might mean that your body is reacting to gluten in the food you eat, which is often seen in conditions like non-celiac gluten sensitivity or celiac disease. This increase could also suggest that your immune system is more sensitive and responding more strongly to substances around you, including gluten in your diet. Keep in mind that factors like eating gluten recently or taking certain medications could affect these levels.
Symptoms of High Levels
Symptoms of high levels of Anti-DGP IgG may include digestive issues such as bloating, diarrhea, or constipation, fatigue, skin rashes, and unexplained weight loss.
If Your Levels are Low
Low levels of Anti-DGP IgG might mean that your body isn't reacting strongly to a part of gluten called deamidated gliadin. This could be because you're not eating much gluten, your body naturally doesn't respond much to it, or certain medications or health issues are affecting your immune system's ability to make these antibodies. Keep in mind that having low Anti-DGP IgG levels doesn't necessarily mean you don't have any gluten-related problems, as people's immune responses can be quite different.
Symptoms of Low Levels
Symptoms of low levels of Anti-DGP IgG are typically absent, as this condition primarily indicates a lack of immune response to gluten, rather than a direct cause of physical discomfort or illness.
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Anti-DGP IgG
Celiac & Gluten Sensitivity
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Blood Spot
The Celiac & Gluten Sensitivity profile helps differentiate between celiac disease and gluten sensitivity by evaluating the serum titers of IgA and IgG for deamidated gliadin peptide, gliadin, and gluten. This is the blood spot version of the test. It is also available as a serum test.
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