The SIBO2-hour Test from Genova Diagnostics is a non-invasive breath test where hydrogen (H2) and methane (CH4) gases are captured following patient ingestion of a lactulose solution.
The test aims to evaluate Small intestinal bacterial overgrowth (SIBO).
Small intestinal bacterial overgrowth (SIBO) occurs when an abnormal
increase in the overall bacterial population occurs in the small intestine. These are usually bacteria not commonly found in that part of the digestive tract.
SIBO commonly may occur when surgery or disease slows the passage of food and waste products in the digestive tract, favoring the growth of certain bacteria.
The excess bacteria may cause gas, burping, bloating, diarrhea, weight loss, and malnutrition. Other symptoms are:
The SIBO-2-hour test measures hydrogen and methane levels on six breaths collected in tubes after consuming a lactulose solution. The tubes are shipped to the lab.
Fasting for 12 hours before the test is required, and patients should not be taking probiotics 24 hours before the test.
Clinicians have the option of a 2 or 3-hour SIBO assessment.
The 3-hour SIBO profile provides insight into gas levels over an extended period. The 3-hour test is recommended for patients with slower gastrointestinal transit or constipation.
Six fasting breath samples are required for the test. Patients will collect the samples following the collection instructions indicated by Genova Diagnostics.
Samples should be taken at baseline and after 20 minutes, 40 minutes, 60 minutes, 90 minutes, and 120 minutes.
*The test is not recommended for individuals who have allergic reactions to lactulose or are on a lactose-restricted diet.
*This test is not appropriate for children under 25 pounds
The 2-hour SIBO assessment is a non-invasive test that evaluates bacterial overgrowth of the small intestine. This test is also available as a 3-hour assessment.
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