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SIBO - 3 Hour

SIBO - 3 Hour

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Genova Diagnostics
SIBO - 3 Hour
Genova Diagnostics
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About the Test

What is the SIBO 3-Hour Test?

The SIBO 3-hour Test from Genova Diagnostics is a non-invasive breath test where hydrogen (H2) and methane (CH4) gases are captured following patient ingestion of a lactulose solution.

The test aims to evaluate Small intestinal bacterial overgrowth (SIBO).

Which Patients is the SIBO 3-Hour Best Used For?

Clinicians have the option of a 2-hour or 3-hour SIBO assessment.

The 3-hour SIBO profile provides insight into gas levels over an extended period. The 3-hour test is recommended for patients with slower gastrointestinal transit or constipation.

Small intestinal bacterial overgrowth (SIBO) occurs when an abnormal increase in the overall bacterial population occurs in the small intestine. These are usually bacteria not commonly found in that part of the digestive tract.

SIBO commonly may occur when surgery or disease slows the passage of food and waste products in the digestive tract, favoring the growth of certain bacteria.

Conditions Commonly Associated with SIBO Include:

  • IBS
  • IBD
  • Celiac Disease
  • Diabetes
  • Fibromyalgia
  • Rosacea
  • Parkinson's Disease
  • Obesity

Common Causes of SIBO

  • Low stomach acid
  • Acid-reducing Medications (PPIs, Tums, Pepcid, Prilosec, immunosuppressants)
  • Gastroparesis
  • Celiac Disease
  • Chronic Constipation
  • Slow digestion/motility
  • Surgery (scar tissue: C section, endometriosis, hysterectomy, tummy tuck)
  • Hypothyroid (low thyroid hormone)
  • Stress (high cortisol)
  • A diet high in sugar, processed carbs, and alcohol
  • Infection (h. Pylori, e. Coli, klebsiella)
  • Food poisoning (most likely with IBS-D/SIBO-D)
  • Structural (ileocecal valve disorder, bariatric)

Symptoms of SIBO

The excess bacteria may cause gas, burping, bloating, diarrhea, weight loss, and malnutrition. Other symptoms are:

  • Bloating worse at the end of the day
  • The patient feels better on a Low FODMAP diet
  • Patients' symptoms get better after antibiotic treatment
  • The patient feels worse after taking probiotics
  • An uncomfortable feeling of fullness or gas immediately after eating

What Does SIBO 3-hour Test Measure?

The SIBO-3-hour test measures hydrogen and methane levels on eight breaths collected in tubes after consuming a lactulose solution. The tubes are shipped to the lab.

Fasting for 12 hours before the test is required, and patients should not be taking probiotics 24 hours before the test.

What Type of Sample is Needed to Complete the SIBO 3- Hour test?

Eight fasting breath samples are required for the test. Patients will collect the samples following the collection instructions indicated by Genova Diagnostics.

Notes

*The test is not recommended for individuals who have allergic reactions to lactulose or are on a lactose-restricted diet.

*This test is not appropriate for children under 25 pounds

About the Test

The 3-hour SIBO assessment is a non-invasive test that evaluates bacterial overgrowth of the small intestine. This longer test is recommended for patients with slower gastrointestinal transit or constipation.

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Lab Test Information
Price
$
210
.00
 $
210.00
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Sample Type
Breath
Shipping Time
5 - 10 days
FedEx
Turnaround Time
21 days
Test Preparation Starts
Up to 14 days before collection
Number of Collection Days
1 day
Methods Used For Processing
GC-TDC/SSS
Lab Certifications
CLIA Certified
CAP Accredited
ISO 15189
COLA Accredited
Order, track, and receive results from 30+ labs in one place.