Add-On: IgE Food Antibodies

The IgE Food Antibodies panel measures IgE antibodies to 19 of the most allergenic foods. This test can be added to any other immunology profile.

What is the Add-on: IgE Food Antibodies by Genova Diagnostics?

This is a serum test that assesses for IgE antibodies produced in response to allergies to the following potentially allergenic foods:

Cow Milk

Codfish

Salmon

Tuna

Brazil Nut

Wheat

Hazelnut

Egg White

Shrimp

Peanut

Oats

Buckwheat

Corn

Soy

Almond

Sesame

Coconut

Rice

Blue Mussel

Additionally, it contains a Total IgE score.

What is the Clinical Relevance of the Add-On: IgE Food Antibodies by Genova Diagnostics?

IgE, an immunoglobulin subclass, plays a pivotal role in the body's allergic responses, particularly immediate hypersensitivity reactions triggered by exposure to foreign substances. These reactions can manifest as symptoms ranging from mild itching and hives to severe anaphylactic shock, depending on the individual's sensitivity and the allergen involved. 

By measuring serum levels of IgE, this test helps identify potential allergic food triggers, aiding in the diagnosis and management of allergic conditions. [1.]

Additionally, IgE-mediated reactions can also manifest with digestive symptoms such as nausea, vomiting, diarrhea, and abdominal pain, highlighting the importance of comprehensive testing for diagnosing allergic conditions involving the gastrointestinal tract. [5.]

In addition to reporting IgE responses to nineteen common food triggers, this Add-On panel contains a Total IgE score, which may help clinicians understand if a patient’s symptoms are being driven by an allergic response outside of the individual allergens tested in this profile.  [2.]

Who Can Benefit from the Add-On: IgE Food Antibodies by Genova Diagnostics?

Individuals experiencing chronic digestive issues: many patients experience frustrating digestive issues such as irritable bowel syndrome (IBS), bloating, gas, diarrhea, or constipation yet receive no answers.  The Add-On: IgE Food Antibodies by Genova Diagnostics may provide insight into food sensitivities that have been linked to gastrointestinal symptoms.  [1.] 

Those suffering from skin conditions: eczema, psoriasis, or chronic urticaria may be linked to food sensitivities that exacerbate these dermatological conditions.  [1.]

People with autoimmune disorders: emerging evidence suggests a potential association between food sensitivities and autoimmune diseases like rheumatoid arthritis, lupus, and Hashimoto's thyroiditis.  [3.]

Individuals experiencing unexplained symptoms without relief: fatigue, brain fog, headaches, and debilitating seasonal allergies are symptoms that are often associated with food sensitivities and immune-mediated reactions.  [4.]

This test may also benefit those seeking to optimize their diet and overall health by identifying potential triggers for immune-mediated responses and making informed dietary modifications accordingly. 

It is important to note that every result should be interpreted within the context of the individual’s health history. 

Collection and Shipping

This is an Add-On test.  For full collection and shipping instructions, click here.

References

[1.] Anvari S, Miller J, Yeh CY, Davis CM. IgE-Mediated Food Allergy. Clin Rev Allergy Immunol. 2019 Oct;57(2):244-260. doi: 10.1007/s12016-018-8710-3. PMID: 30370459.

[2.] Chung D, Park KT, Yarlagadda B, Davis EM, Platt M. The significance of serum total immunoglobulin E for in vitro diagnosis of allergic rhinitis. Int Forum Allergy Rhinol. 2014 Jan;4(1):56-60. doi: 10.1002/alr.21240. Epub 2013 Nov 12. PMID: 24227797.

[3.] Coucke F. Food intolerance in patients with manifest autoimmunity. Observational study. Autoimmun Rev. 2018 Nov;17(11):1078-1080. doi: 10.1016/j.autrev.2018.05.011. Epub 2018 Sep 11. PMID: 30213697.

[4.] Gargano D, Appanna R, Santonicola A, De Bartolomeis F, Stellato C, Cianferoni A, Casolaro V, Iovino P. Food Allergy and Intolerance: A Narrative Review on Nutritional Concerns. Nutrients. 2021 May 13;13(5):1638. doi: 10.3390/nu13051638. PMID: 34068047; PMCID: PMC8152468.

[5.] Pearson JS, Niven RM, Meng J, Atarodi S, Whorwell PJ. Immunoglobulin E in irritable bowel syndrome: another target for treatment? A case report and literature review. Therap Adv Gastroenterol. 2015 Sep;8(5):270-7. doi: 10.1177/1756283X15588875. PMID: 26327917; PMCID: PMC4530434.