The flathead lobster (Thenus orientalis) is a distinctive slipper lobster known for its flattened body and wide distribution across the Indian and Pacific Oceans.
Valued ecologically and commercially, this species plays a key role in benthic ecosystems and is a popular seafood prized for its sweet-tasting meat.
Flathead lobster is a type of slipper lobster, of which there are at least 90 types.
The flathead lobster, Thenus orientalis, is a type of slipper lobster with a flattened body. It is found across the Indian and Pacific Oceans and can grow up to 280 mm long and weigh over 0.5 kg.
Flathead lobsters live on sandy sea floors and are nocturnal hunters. During the day, they burrow in sand or hide in reef crevices.
Their diet includes molluscs (like mussels and limpets), small crabs, shrimps, worms, and sea urchins. Predators include groupers, octopuses, and triggerfish.
They reach maturity between 1 and 3 years. Females can carry between 26,000 and 100,000 eggs under their bodies, which hatch into tiny larvae that drift for up to 11 months. Very few survive to adulthood, which can live up to 10 years.
Flathead lobster is often used in chowders, salads, in Asian recipes, and in other dishes where rock lobster might be used. The meat, coming from the tail, is considered sweet.
While considered a delicious seafood, some people may need to use caution when eating flathead lobster, or avoid it.
Crustacean shellfish, including flathead lobsters, are among the most common causes of food allergies. These allergies can trigger reactions ranging from mild symptoms like itching or hives to severe, potentially life-threatening anaphylaxis.
Importantly, cross-reactivity between crustaceans often occurs. Due to shared allergenic proteins, patients with shrimp or crab allergies may also react to flathead lobster.
Clinicians should advise patients with crustacean allergies to avoid all related species unless specifically tested (see below).
Flathead lobsters, like other seafood, can be a source of foodborne illness if not handled properly.
Shellfish poisoning is caused by toxins from algae blooms that accumulate in shellfish like mussels, clams, oysters, crabs, and lobsters.
Symptoms—such as numbness, nausea, or confusion—can appear within hours and may be severe or even fatal, so prompt medical care is essential if illness occurs after eating shellfish.
In addition, bacterial contaminants such as Vibrio species or viruses like norovirus can pose a risk if the lobster is undercooked or exposed to contaminated water.
While not specific to flathead lobster, heavy metal accumulation is a general concern with seafood. Flathead lobsters may accumulate substances like mercury or arsenic from their environment through a process known as bioaccumulation.
Regulatory agencies routinely monitor heavy metal levels in seafood, but clinicians should be mindful when advising high-risk populations, such as pregnant individuals or those with kidney issues.
Food allergies and food sensitivities are different immune responses to food. Whether a person has a food allergy or food sensitivity, the proteins in a particular food are often (but not always) responsible for triggering the immune system's reaction.
Food allergies, typically IgE-mediated, cause immediate, sometimes severe reactions like anaphylaxis within minutes to hours of eating the food, often triggered by common allergens like nuts, seafood, or dairy.
On the other hand, food sensitivities are more common and involve delayed non-IgE-mediated immune reactions, such as gastrointestinal discomfort or skin issues, and usually occur hours or days after consuming the food. They may involve an IgG-mediated immune response, and other immune-mediated chemicals may also be present.
While food allergies can cause life-threatening reactions like anaphylaxis and are often identified early, food sensitivities are not life-threatening and can be managed with dietary changes.
Both are triggered when the immune system mistakenly identifies food proteins as harmful, but food allergies involve an immediate IgE response, while food sensitivities are due to a delayed immune reaction.
Food sensitivity testing such as this panel identifies various immune reactions, helping clinicians pinpoint which foods may trigger symptoms.
This testing can be helpful when it’s important to differentiate food sensitivities from food allergies, as they require different management strategies. Unlike traditional allergy testing, which focuses on immediate responses, food sensitivity testing can reveal delayed, less obvious reactions.
Different companies offer different panels, which may assess various biomarkers. Increasingly, a combination of the following biomarkers are seen:
IgG, IgA, IgM, and IgE antibodies are the primary markers tested for food sensitivities. IgG is a commonly tested antibody in food sensitivity panels, as it reflects a delayed, chronic immune response.
IgA and IgM are also assessed regarding mucosal immunity and initial immune responses, respectively.
IgE is typically tested in food allergy testing, but it can sometimes be part of food sensitivity panels if a clinician suspects allergic reactions and sensitivities.
Complement Markers may also be tested in some panels, offering insights into inflammation and immune system activation.
Food sensitivity panels often test for common foods like dairy, gluten, soy, eggs, nuts, and shellfish. These foods are frequently implicated in immune reactions due to their protein structures, which can provoke an immune response in sensitive individuals.
However, many companies now offer testing for additional foods to help clinicians craft more personalized patient food plans. The foods tested will depend on the patient’s history, symptoms, and dietary considerations.
Test results typically include a range of reactivity, from low to high. Low reactivity indicates minimal immune involvement and may not be clinically significant.
High reactivity suggests that the food is likely a trigger for symptoms. It’s essential to interpret these results in the context of the patient's clinical presentation.
Positive results are not definitive diagnoses but guide further clinical action, such as elimination diets or further testing.
Food sensitivity testing is most useful when patients present with chronic, unexplained symptoms that don’t fit into conventional diagnostic categories. Conditions like irritable bowel syndrome (IBS), autoimmune disorders, and other inflammatory conditions may be associated with food sensitivities.
Testing may be especially useful when symptom patterns or patient history suggest a dietary trigger but when traditional allergy testing has been negative.
Food sensitivities are often tied to gut health and inflammation. Leaky gut syndrome, where the intestinal lining becomes permeable, is frequently linked with food sensitivities. Identifying specific triggers can help reduce systemic inflammation and improve gut function.
While food sensitivity testing can be highly informative, there are limitations.
False positives and negatives can occur, as these tests may detect un clinically significant immune reactions. Additionally, sensitivity testing is not a one-size-fits-all solution—other factors, such as gut microbiota and leaky gut, should also be considered when interpreting results.
Finally, food sensitivity testing remains a controversial area, with some mainstream practitioners questioning its validity.
As with any assessment or treatment, the potential benefits should be weighed against the risks for every patient.
Click here to compare testing options and order testing for food allergies and sensitivities.
Allergy Blood Test. (2024). Medlineplus.gov. https://medlineplus.gov/lab-tests/allergy-blood-test
Fish Poisoning in Travelers: Ciguatera and Scombroid | Travelers’ Health | CDC. (2019). Cdc.gov; CDC.gov. https://wwwnc.cdc.gov/travel/page/fish-poisoning-ciguatera-scombroid
FIT 132 + Gut Barrier Panel by KBMO Diagnostics. (2020). Rupa Health. https://www.rupahealth.com/lab-tests/fit-132
Greenan, S. (2021, November 17). The 8 Most Common Signs Of A Food Sensitivity. Rupa Health. https://www.rupahealth.com/post/a-functional-medicine-approach-to-food-sensitivities-testing-and-treatment
Iwamoto M, Ayers T, Mahon BE, Swerdlow DL. Epidemiology of seafood-associated infections in the United States. Clin Microbiol Rev. 2010 Apr;23(2):399-411. doi: 10.1128/CMR.00059-09. PMID: 20375359; PMCID: PMC2863362.
Laumonnier, Y., Korkmaz, R. Ü., Nowacka, A. A., & Köhl, J. (2023). Complement-mediated immune mechanisms in allergy. European journal of immunology, 53(10), e2249979. https://doi.org/10.1002/eji.202249979
Lopez CM, Yarrarapu SNS, Mendez MD. Food Allergies. [Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482187/
Lotfi Rabaoui, Lamia Yacoubi, Lin, Y.-J., Joydas, T. V., Qurban, M. A., Panickan Premlal, Gopalan, J., Nazeer, Z., Manambrakat Vijayakumaran, Khan, S. A., & Roa-Ureta, R. H. (2022). Ecology, life history, and fisheries potential of the flathead lobster (Thenus orientalis) in the Arabian Gulf. Fishery Bulletin, 120(2), 125–137. https://doi.org/10.7755/fb.120.2.
Mayo clinic. (2019). Shellfish allergy - Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/shellfish-allergy/symptoms-causes/syc-20377503
McLendon K, Sternard BT. Anaphylaxis. [Updated 2023 Jan 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482124/
Scheurer, S., Junker, A. C., He, C., Schülke, S., & Toda, M. (2023). The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses. Current allergy and asthma reports, 23(10), 589–600. https://doi.org/10.1007/s11882-023-01105-x
Shakoor, Z., AlFaifi, A., AlAmro, B., AlTawil, L. N., & AlOhaly, R. Y. (2016). Prevalence of IgG-mediated food intolerance among patients with allergic symptoms. Annals of Saudi medicine, 36(6), 386–390. https://doi.org/10.5144/0256-4947.2016.386
Slipper Lobsters: Species & Distribution. (n.d.). https://lmmanetwork.org/wp-content/uploads/2021/08/Anon_12_ISFC_21_SlipperLobsters.pdf
Stanford, J. (2024, May 23). The Top 5 Food Sensitivities and Intolerances You Will See in Your Practice. Rupa Health. https://www.rupahealth.com/post/common-food-sensitivities-intolerances
Vojdani A. (2009). Detection of IgE, IgG, IgA and IgM antibodies against raw and processed food antigens. Nutrition & metabolism, 6, 22. https://doi.org/10.1186/1743-7075-6-22
Zhuzzhassarova G, Azarbayjani F, Zamaratskaia G. Fish and Seafood Safety: Human Exposure to Toxic Metals from the Aquatic Environment and Fish in Central Asia. Int J Mol Sci. 2024 Jan 27;25(3):1590. doi: 10.3390/ijms25031590. PMID: 38338869; PMCID: PMC10855114.