Pregnanediol

High levels of pregnanediol in your urine could indicate that your body is producing or processing an excess amount of progesterone. This could be due to a variety of reasons. For instance, you might be pregnant, as progesterone levels naturally increase during pregnancy. Alternatively, you could be taking certain medications that affect hormone levels, such as hormone replacement therapy or certain types of birth control. High levels could also be a sign of a condition like polycystic ovary syndrome (PCOS), which can cause an imbalance in female sex hormones. It's also possible that your body is simply more efficient at metabolizing progesterone, leading to higher levels of pregnanediol.

Symptoms of high levels of pregnanediol could include irregular menstrual cycles, changes in mood, bloating, and fatigue.

Low levels of pregnanediol in your urine could mean that your body isn't processing progesterone as well as it should be. Progesterone is a hormone that's really important for things like your menstrual cycle and pregnancy. So, if your body isn't breaking it down properly, it could be a sign of issues with your reproductive system. Certain conditions, like polycystic ovary syndrome (PCOS), can cause this. Also, some medications, like birth control pills or hormone replacement therapy, can affect your progesterone levels and, in turn, your pregnanediol levels. So, if you're taking any of these, it could be a factor. Environmental factors, like stress or a poor diet, could also play a role.

Symptoms of low levels of pregnanediol might not be obvious. However, since it's linked to progesterone, you might experience symptoms related to low progesterone levels. These could include irregular or missed periods, mood changes, headaches, and difficulty getting pregnant.