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Reference Guide
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Hb S
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Hemoglobin S

What's 
Hb S
?
Hemoglobin S (Hb S) is a different type of hemoglobin, which is the protein in your red blood cells that carries oxygen. It is caused by a genetic change that alters the structure of the hemoglobin molecule. Hb S is mainly linked to sickle cell disease, a condition named after the unusual 'sickle' or crescent shape of the red blood cells it creates. This shape change happens because of how Hb S molecules act when they let go of their oxygen, making the cells stiff and sticky. This can disrupt the smooth flow of blood and oxygen throughout the body, affecting various functions.
If Your Levels Are High
Elevated levels of Hb S might suggest a genetic tendency towards sickle cell trait or disease. This means your body produces an unusual type of hemoglobin, which is the protein in red blood cells responsible for carrying oxygen. The presence of Hb S can cause these cells to change shape, potentially making it harder for blood and oxygen to flow smoothly throughout your body. This could affect various functions and your overall well-being. Certain situations, like being at high altitudes or engaging in intense physical activity, could make these effects worse. It's also important to note that some medications or treatments, such as hydroxyurea or blood transfusions, might influence the levels of Hb S in your blood.
Symptoms of High Levels
Symptoms of high levels of Hb S may include fatigue, shortness of breath, rapid heart rate, and episodes of pain, often in the hands and feet.
If Your Levels are Low
Low levels of Hemoglobin S (Hb S) might mean that your body isn't producing this specific type of hemoglobin in large amounts. This could be due to your genes, as not everyone has the gene mutation that leads to Hb S production. It's also possible that your body is effectively managing its hemoglobin levels, creating less Hb S while still carrying enough oxygen throughout your body. Some medications or dietary factors could also play a role in influencing Hb S production. Keep in mind that having low Hb S levels doesn't necessarily mean you're at risk for any specific health issues.
Symptoms of Low Levels
Symptoms of low levels of Hb S are typically not noticeable, as this condition does not generally cause any specific physical signs or discomfort.

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