Mosaic Diagnostics (formerly Great Plains lab)
Mosaic Diagnostics (formerly Great Plains lab)
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About the Test

What is the GPL-Tox Test?

GPL-TOX is a comprehensive pollutant exposure test screening for 173 environmental toxins through 18 metabolites, including Tiglyglycine, a marker for mitochondrial damage often seen in chronic toxic exposure. This test applies the power of advanced mass spectrometry (MS/MS), which is necessary to detect lower levels of certain genetic, mitochondrial, and toxic chemical markers that conventional mass spectrometry often misses.

Which Patients is the GPL-Tox Test Best Used For?

Every day, we are exposed to hundreds of toxic chemicals through pharmaceuticals, pesticides, packaged foods, household products, and environmental pollution. Growth in industrial manufacturing, fossil fuel consumption, and chemical-intensive agricultural methods has dramatically increased the scale and complexity of humans’ exposure to environmental toxins, which carry health risks ranging from skin irritation to deadly illness.

What Type of Sample is Needed to Complete the GPL Tox Test?

10 mL of first-morning urine before food or drink is suggested. Fasting for 24 hours may increase the excretion of toxic chemicals from the adipose tissue.

*Note: The test is optimal for follow-up testing to ensure that therapies have been successful.

About the Test

The GPL-TOX is a toxic non-metal chemical profile that screens for the presence of 173 different toxic chemicals using 18 different metabolites, all from a single urine sample. It also includes Tiglylglycine (TG), a marker for mitochondrial damage, which is often seen in chronic toxic chemical exposure.

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Lab Test Information
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Sample Type
Shipping Time
3 - 5 days
Turnaround Time
10 days
Test Preparation Starts
Up to 12 hours before collection
Number of Collection Days
1 day
Methods Used For Processing
Lab Certifications
CLIA Certified
CAP Accredited
ISO 15189
COLA Accredited
Order, track, and receive results from 30+ labs in one place.