The GI Effects® Fundamentals Test from Genova Diagnostics evaluates the overall health of the GI tract. The main biomarkers from the GI Effects Fundamentals Profile provide key clinical information for three main gastrointestinal functional areas: Digestion/Absorption, Inflammation/Immunology, and Gut Microbiome.
This is the 1-day version of the test; it is also available as a 3-day test.
An imbalance of the normal gut microbiota or dysbiosis may lead to gastrointestinal conditions such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), and wider systemic alterations such as celiac disease, cardiovascular disease, neurological disorders, malnutrition, skin conditions, autoimmune disorders, immune system imbalances, and multiple inflammatory disorders.
The GI Effects Fundamentals Test involves the analysis of the stool profile with optional add-on tests to allow the physician the selection of relevant biomarkers according to each patient, including parasitology and others.
The GI Effects® Fundamentals Test from Genova Diagnostics informs the possible cause of common gastrointestinal symptoms such as bloating, indigestion, gas, abdominal pain, diarrhea, and constipation.
The minimum biomarkers measured by the test are Pancreatic Elastase-1, products of Protein Breakdown, Fecal Fat, Calprotectin, Eosinophil Protein X, Fecal Occult Blood, Metabolic indicators, Bacteria and mycology cultures, Bacteria and mycology sensitivities.
There are additional biomarkers that the treating physician can select: Parasitology test, Secretory IgA*, Campylobacter, Clostridium difficile, Escherichia coli, Helicobacter pylori*, Macroscopic Exam for Worms, KOH Preparation for Yeast, and Zonulin Family Peptide.
An at-home stool sample is required.
Physicians may want to use the GI Effects Fundamentals test to profile gastrointestinal biomarkers to support the development of strategic interventions.
The GI Effects Fundamentals fecal biomarker panel in the stool sample assesses multiple functional areas contributing to symptoms. For example, diarrhea can originate from several causes, including inflammation, food sensitivities, allergies, or pancreatic exocrine insufficiency. The physician may want to order the test to rule out the cause of the symptoms.
The GI Effects® Fundamentals profile provides a cursory evaluation of the overall health of the GI tract, including insights into digestion/absorption, inflammation/immune response, gut microbial metabolites, and potential dysbiotic or pathological organisms. This is the 1-day version of the test; it is also available as a 3-day test.