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Zonulin Add-On

Zonulin Add-On

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KBMO Diagnostics
Zonulin Add-On
KBMO Diagnostics
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About the Test

Our New Unique Zonulin Assay is Now Included on the FIT 132 and FIT 176

We are excited to introduce another unique assay to the market, Dr Brent Dorval and Dr Alessio Fasano have partnered to create the only Zonulin assay which does not cross react with haptoglobin, properdin or any complement fragments. They have achieved this by creating a unique recombinant zonulin protein. By measuring the Zonulin antibody It makes the assay also uniquely stable to avoid the fluctuations reported in Zonulin protein assays. The assay also has similar positivity rates as seen in Fasano’s letter to the Lancet.

What is Zonulin?

Zonulin is a protein that is synthesized in intestinal cells and liver cells. It is a key biomarker for intestinal permeability and is the only regulator of intestinal permeability that is reversible. Zonulin is one of three ways the FIT test can diagnose a leaky gut, along with finding a sensitivity to Candida and multiple Food Sensitivities. It is estimated that anywhere between 50 and 100 percent of food intolerance sufferers have increased intestinal permeability.

Which Patients is the Zonulin Test Best Used For?

Increased intestinal permeability can be caused by food allergies and sensitivities, stress, infections, and low stomach acid, among other causes. Elevated levels of Zonulin are associated with Celiac Disease, Autoimmune disease, and Multiple Sclerosis, in addition to other chronic illnesses.

In a healthy gut, there are healthy cell junctions and good nutrient absorption. In a leaky gut, however, the Villi are damaged, there is poor absorption and the cell junctions are loose. This means that bacteria and unwanted items can pass through the gut, as seen in the picture to below.

Zonulin Testing is best performed with the patient’s first FIT Test to provide a baseline for the Zonulin levels. This gives patients the opportunity to track their progress after implementing an elimination diet based on the FIT Test results. We recommend retesting when you retest your FIT.

About the Test

This is a single-marker add-on test measuring zonulin. It can be added to the FIT 44 or FIT 22.

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Lab Test Information
Price
$
75
.00
 $
75.00
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Lab Company
KBMO Diagnostics
Sample Type
Blood Spot
Shipping Time
3 - 7 days
UPS
Turnaround Time
10 days
Test Preparation Starts
No test preparation required
Number of Collection Days
1 day
Methods Used For Processing
ELISA
Lab Certifications
CLIA Certified
CAP Accredited
ISO 15189
COLA Accredited
Order, track, and receive results from 30+ labs in one place.